Virtual Lecture: Late-Stage Functionalizations

Lecture held on: April 28, 2022

Presenter

Prof. Tobias Ritter – Director of Max Planck Institut für Kohlenforschung, Mülheim an der Ruhr, Germany

Late-stage functionalization reactions should reliably functionalize already complex molecules to quickly access value-added molecular diversity. Late-stage functionalization is desirable in many areas of discovery such as in drug or agrochemical development and a requirement in other areas such as the synthesis of positron emission tomography (PET) tracers. Prof. Ritter described the development of novel, modern highly selective reactions in late-stage functionalization, as well as their application in transition metal catalyzed and photoredox reactions, with a focus on the synthesis of ¹⁸F and ¹⁹F containing complex small molecules. In particular, Prof. Ritter discussed the development of a broadly useful new C-H functionalization reaction to create molecular complexity for applications in catalysis, drug discovery, and medicine.